Table 3.
Histopathological Assessment of Liver Samples After MSC Treatments
| Saline | AdGFP-MSCs | AdIGF-I-MSCs | |
|---|---|---|---|
| Periportal or periseptal hepatitis | 3.0±0.00 | 2.2±0.20 | 2.2±0.20 |
| Confluent necrosis | 3.4±0.40 | 2.6±0.40 | 2.2±0.2* |
| Focal lytic necrosis, apoptosis and focal inflammation | 2.6±0.24 | 2.2±0.20 | 2.2±0.45 |
| Portal inflammation | 3.4±0.24 | 2.4±0.24 | 2.6±0.24 |
| Fibrosis | 4.6±0.24 | 4.0±0.32 | 2.8±0.2**σ |
| Knodell score | 17.0±0.45 | 12.5±0.64* | 11.5±0.29** |
Knodell scores (mean±SD) were calculated by an expert pathologist. *σP<0.05; **P<0.01; * versus saline; σ versus AdGFP-MSCs.