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. Author manuscript; available in PMC: 2015 Mar 11.
Published in final edited form as: J Invest Dermatol. 2008 Oct 2;129(3):742–751. doi: 10.1038/jid.2008.295

Figure 1. Targeting IL-13 to the skin.

Figure 1

(a) Schematic construct of TRE-Tight-IL-13. (b) Tissue specificity of IL-13 expression in Tg(+) mice as determined by RT–PCR. The experiments were started by withdrawing Dox and total RNA from different tissues was analyzed for IL-13 mRNA expression. (c) IL-13 mRNA expression in the skin of Tg(+) mice in comparison with Tg(−) mice 6 weeks off Dox. (d) IL-13 protein in the skin extract 8 weeks after Dox withdrawal (n = 36, each group).