Effects of media condition and mixed co-culture on cartilage matrix production. (A) DNA, (B) sGAG, and (C) collagen content per wet weight in mixed co-culture at day 21 with or without TGF-β3 supplementation. Data presented as mean±SD (n=3 samples/group). * and ^ represent significance versus OAC and ADSC control under the same media condition, respectively; *p<0.05, **p<0.01, and ***p<0.001.