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Summary of NF-κB decoy ODN effects on MSCs in the presence of UHMWPE particles. Suppression of NF-κB activity by decoy ODN may protect MSCs from wear particle-induced bone loss using three distinct pathways, including (1) suppressing the immune response, (2) enhancing osteogenesis, and (3) suppressing osteoclastogenesis. Color images available online at www.liebertpub.com/tea
