Figure 1.

Domain representation of full-length Cwp84. The signal peptide is shown in grey, the propeptide in red, the cysteine protease domain in green, the lectin-like domain in cyan and the cell-wall-binding domains in purple. The catalytic dyad (Cys116 and His262) and oxyanion hole-forming glutamine (Gln110) are highlighted in pink, with the calcium-binding residues (Leu339, Glu448, Lys460 and Asn487) in orange. The fragment with its structure discussed here, residues 92–497, is bracketed; this complements the previously described structure consisting of residues 33–497 (Bradshaw et al., 2014 ▶).