Table III.

Univariate and multivariate survival analysis of clinicopathological factors for the overall survival rate of 186 patients with non-small cell lung cancer.

					95% CI
Characteristics	β	SE	Wald	HR	Lower	Upper	P-value
Univariate
Gender	0.100	0.148	0.459	1.105	0.827	1.477	0.498
Age, years	0.349	0.155	5.071	1.418	1.046	1.921	0.024a
Smoking status	0.103	0.177	0.340	1.109	0.784	1.569	0.560
Tumor size, cm	0.242	0.149	2.634	1.274	0.951	1.708	0.105
Clinical stage	0.588	0.151	15.198	1.801	1.340	2.420	0.000b
Differentiation	0.229	0.105	4.746	1.257	1.023	1.544	0.029a
CEA	0.023	0.147	0.024	1.023	0.767	1.365	0.876
Pathological subtype	0.050	0.147	0.116	1.051	0.788	1.404	0.734
LN metastasis	0.478	0.151	10.029	1.614	1.200	2.170	0.002b
IMP3	0.618	0.169	13.382	1.856	1.333	2.585	0.000b
Multivariate
Age, years	0.283	0.157	3.251	1.328	0.976	1.806	0.071
Clinical stage	0.551	0.155	12.583	1.734	1.279	2.351	0.000b
Differentiation	0.137	0.112	1.511	1.147	0.922	1.428	0.219
LN metastasis	0.359	0.156	5.277	1.431	1.054	1.944	0.022a
IMP3	0.475	0.178	7.096	1.608	1.134	2.281	0.008b

Statistical analyses were performed using Cox’s proportional hazard regression model.

^aP<0.05 and

^bP<0.01.

CI, confidence interval; HR, hazard ratio; SE, standard error; CEA, carcinoembryonic antigen; LN, lymph node.