Table IV.
Genotype frequencies of ERCC1 and ERCC2 polymorphisms of control group (n=97) and osteosarcoma patients (n=28).
| Variants | Genotypes | Controls, n (%) | Patients, n (%) | OR (95% CI) | P-valuea |
|---|---|---|---|---|---|
| ERCC1 rs11615 | GG | 59 (60.8) | 16 (57.2) | 1.00 | |
| GA | 32 (33.0) | 9 (32.1) | 1.04 (0.41–2.61) | 0.94 | |
| AA | 6 (6.2) | 3 (10.7) | 1.84 (0.41–8.20) | 0.42 | |
| GG/GA | 91 (93.8) | 25 (89.3) | 1.16 (0.50–2.73) | 0.73 | |
| ERCC2 rs13181 | AA | 64 (66.0) | 21 (75.0) | 1.00 | |
| AC | 31 (31.9) | 7 (25.0) | 0.69 (0.26–1.79) | 0.44 | |
| CC | 2 (2.1) | 0 (0.0) | 0.60 (0.03–12.99) | 0.42 | |
| AA/AC | 95 (97.9) | 28 (100.0) | 0.65 (0.25–1.68) | 0.37 | |
| ERCC2 rs1799793 | CC | 68 (70.1) | 21 (75.0) | 1.00 | |
| CT | 8 (8.3) | 3 (10.7) | 1.21 (0.29–4.99) | 0.79 | |
| TT | 21 (21.6) | 4 (14.3) | 0.62 (0.19–1.99) | 0.42 | |
| CC/CT | 76 (78.4) | 24 (85.7) | 0.78 (0.29–2.04) | 0.61 |
a
χ2 or Fisher’s exact test.