Table VI.
Variants | Genotypes | Controls, n (%) | Patients, n (%) | OR (95% CI) | P-valuea |
---|---|---|---|---|---|
ERCC1 rs11615 | GG | 40 (54.1) | 38 (53.5) | 1.00 | |
GA | 27 (36.5) | 28 (39.4) | 1.09 (0.55–2.18) | 0.80 | |
AA | 7 (9.4) | 5 (7.1) | 0.75 (0.22–2.57) | 0.65 | |
GG/GA | 67 (90.6) | 66 (92.9) | 1.02 (0.53–1.96) | 0.95 | |
ERCC2 rs13181 | AA | 45 (60.8) | 49 (69.1) | 1.00 | |
AC | 27 (36.5) | 19 (26.7) | 0.65 (0.32–1.32) | 0.23 | |
CC | 2 (2.7) | 3 (4.2) | 1.38 (0.22–8.62) | 0.73 | |
AA/AC | 72 (97.3) | 68 (95.8) | 0.69 (0.35–1.38) | 0.30 | |
ERCC2 rs1799793 | CC | 54 (72.9) | 54 (76.0) | 1.00 | |
CT | 1 (1.4) | 9 (12.7) | 9.00 (1.10–73.50) | 0.01b | |
TT | 19 (25.7) | 8 (12.3) | 0.42 (0.17–1.04) | 0.06 | |
CC/CT | 55 (74.3) | 63 (88.7) | 0.85 (0.40–1.79) | 0.67 |
χ2 or Fisher’s exact test.
Deviated from Hardy-Weinberg equilibrium.