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. 2015 Feb 4;35(4):925–931. doi: 10.3892/ijmm.2015.2090

Figure 3.

Figure 3

Effect of treatment with 10−11 to 10−8 M [D-Tyr6-β-Ala11,Phe13,Nle14] bombesin6–14 and insulin on PKB, p70s6K, p42/p44 MAPK and p90RSK1 phosphorylation in cultured primary human myocytes from patients with obesity and type 2 diabetes (OB/T2D) incubated for 3 min. (A) Representative immunoblots. (B) Quantitative analysis of enzyme phosphorylation levels; values (means ± SEM) are relative to the respective paired control obtained form cellular samples incubated in the absence of the peptide corresponding to patients with OB/T2D (n=5). *p<0.02 vs. control; †p<0.0001 vs. treatment with insulin.