FIG. 6.

Hematoxylin and eosin composite of regenerated bone across treatment groups. FT, fibrous tissue; NB, native bone; RB, regenerated bone; white arrow represents defect margin; white asterisks represent ADM scaffold. Bright-field images obtained with 10× objective. Note osteointegration of bone at the defect margins across biopatterned growth factor therapy groups. Cement lines and reversal lines are present within the biopatterned growth factor therapy growth, depicting bone remodeling. Note the purple staining of lacunae with chondrocytes in (B) depicting endochondral ossification. Color images available online at www.liebertpub.com/tea