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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Neuropharmacology. 2014 May 20;85:91–103. doi: 10.1016/j.neuropharm.2014.05.005

Fig. 2.

Fig. 2

Differential effects of RO0711401 and VU0360172 on the incidence of SWDs on days 1 and 10 of treatment in WAG/Rij rats. Rats were treated s.c. twice daily with RO0711401 (10 mg/kg), VU0360172 (3 mg/kg) or their respective vehicles. SWD incidence measured at baseline (time 0) and in the first 5 h post injection on day 1 and 10 of treatment are shown in (A) and (B), respectively. Mean duration of SWDs is shown in (C) and (D); spontaneous motor activity is shown in (E) and (F). Values are means + S.E.M. P < 0.05 vs. the respective vehicles (*) or vs. VU0360172 (#). Statistical analysis is detailed in the Results session.