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. 2015 Mar 11;10(3):e0118512. doi: 10.1371/journal.pone.0118512

Fig 5. Effect of in vivo treatment with oleamide on microglial anti-inflammatory activity.

Fig 5

CD-1 mice (n = 7/group) were orally given 50 mg/kg of oleamide once a day for 3 days and then injected intracerebroventricularly with either saline or 0.25 mg/kg of LPS. A and B, Quantification of TNF-α in the cerebral cortex and hippocampus, respectively. C and D, Quantification of MIP-1α in the cerebral cortex and hippocampus, respectively. E and F, The ratio (%) of TNF-α-positive or MIP-1α-positive cells to CD11b-positive cells. G, H, and I, Expression of I-A/I-E, CD68, and PDL-2, respectively, in CD11b single-positive cells. Error bars represent the means ± SEM of 7 mice per group. *p < 0.05 and **p < 0.01.