Table 4. Time-dependent hazard ratios for the 11 donor risk variables included in the IHTSA model.
Hazard ratio at 1 year | Hazard ratio at 5 years | Hazard ratio at 10 years | ||||
---|---|---|---|---|---|---|
Demographic data | ||||||
Age (per 11 years) | 1.17 | (1.172–1.173) | 1.11 | (1.111–1.112) | 1.08 | (1.075–1.075) |
Female gender | 1.02 | (1.019–1.020) | 1.04 | (1.038–1.039) | 1.04 | (1.040–1.042) |
Weight (per 10 kg) | 0.99 | (0.994–0.994) | 1.02 | (1.018–1.018) | 1.03 | (1.030–1.030) |
Duration of ischemia (per 42 min) | 1.03 | (1.025–1.026) | 1.01 | (1.008–1.008) | 1.00 | (0.997–0.998) |
CODD: Head trauma | 0.90 | (0.896–0.898) | 1.00 | (0.998–1.000) | 1.09 | (1.085–1.087) |
CODD: Cerebrovascular event | 0.89 | (0.890–0.891) | 0.97 | (0.969–0.971) | 1.05 | (1.050–1.052) |
Donor blood group | ||||||
B | 1.05 | (1.044–1.046) | 1.07 | (1.070–1.073) | 1.09 | (1.092–1.096) |
AB | 1.13 | (1.126–1.129) | 1.16 | (1.154–1.157) | 1.14 | (1.135–1.140) |
O | 0.96 | (0.960–0.961) | 0.98 | (0.983–0.985) | 0.99 | (0.991–0.993) |
Recipient-donor weight ratio (per 0.14 units) | 1.02 | (1.015–1.015) | 1.01 | (1.014–1.014) | 1.02 | (1.016–1.016) |
Recipient-donor height ratio (per 0.04 units) | 0.99 | (0.991–0.991) | 1.00 | (0.996–0.996) | 1.00 | (0.999–0.999) |
The data are hazard ratio together with 95% confidence interval for the different time points estimated from 10,000 bootstrap samples. CODD, cause of donor death; ITHSA, international heart transplantation survival algorithm.