Table 5. Comparison of C-index between different risk models used to predict overall survival.
| C-index (95% CI) | ||||
|---|---|---|---|---|
| DC | IVC | TVC | NTTD | |
| n = 41,780 | n = 8,569 | n = 6,276 | n = 1,285 | |
| IHTSA | 0.60 (0.59–0.60) | 0.59 (0.58–0.60) | 0.65 (0.63–0.66) | 0.59 (0.56–0.62) |
| DRI | 0.54 (0.54–0.55) † | 0.54 (0.53–0.55) † | 0.58 (0.56–0.60) † | 0.55 (0.52–0.58)* |
| IMPACT | 0.56 (0.55–0.57) † | 0.55 (0.54–0.56) † | 0.63 (0.61–0.65) | 0.52 (0.49–0.56) † |
| RSS | 0.56 (0.56–0.57) † | 0.56 (0.55–0.57) † | 0.64 (0.62–0.65) | 0.54 (0.51–0.58)* |
*p < 0.05
†p ≤ 0.001 compared with ITHSA. CI, confidence interval; DC, derivation cohort; DRI, donor risk index for transplantation (reported in the paper by Weiss et al. [6]); IMPACT, index for mortality prediction after cardiac transplantation (reported in the paper by Weiss et al. [7]); ITHSA, international heart transplantation survival algorithm; IVC, internal validation cohort; NTTD, Nordic thoracic transplantation database; RSS, risk-stratification score (reported in the paper by Hong et al. [9]); TVC, temporal validation cohort.