Table 1.
Statistics from linear models plotted in Figure 10. Although the raw and structurally predicted CBF values showed strong trends with age, the trends for the residual CBF was more variable. Residual CBF was strongly associated with age in the hippocampus and precuneus, but less so in superior occipital cortex and the precentral gyrus. This may suggest that there is a lesser degree of functional specialization in the precentral gyrus and occipital cortex than in hippocampus and precuneus throughout adolescence. Slope is given in units of CBF (ml/100g/min) per year.
| Raw CBF
|
Structural CBF
|
Residual CBF
|
||||
|---|---|---|---|---|---|---|
| Slope | p-value | Slope | p-value | Slope | p-value | |
| Left Hippocampus | −1.62±0.32 | 1.12 × 10−6 | −2.87±0.42 | 1.41 × 10−10 | 1.25±0.24 | 9.09 × 10−7 |
| Right Hippocampus | −1.28±0.34 | 2.3 × 10−4 | −2.89±0.42 | 10−10 | 1.61±0.24 | 3.99 × 10−10 |
| Left Precuneus | −4.28±0.55 | 7.27 × 10−13 | −2.8±0.41 | 1.08 × 10−10 | −1.48±0.24 | 4.41 × 10−9 |
| Right Precuneus | −4.09±0.54 | 2.04 × 10−12 | −2.84±0.4 | 5.69 × 10−11 | −1.25±0.26 | 3.7 × 10−6 |
| Left Precentral | −2.37±0.56 | 4.37 × 10−5 | −2.56±0.4 | 1.56 × 10−9 | 0.2±0.25 | 0.42 |
| Right Precentral | −2.2±0.55 | 10−4 | −2.55±0.4 | 2.05 × 10−9 | 0.35±0.25 | 0.16 |
| Left Occipital | −2.1±0.47 | 1.73 × 10−5 | −2.68±0.4 | 2.53 × 10−10 | 0.58±0.24 | 0.02 |
| Right Occipital | −2.64±0.47 | 9.79 × 10−8 | −2.65±0.4 | 6.76 × 10−10 | 0.01±0.23 | 0.96 |
| DMN | −3.42±0.47 | 1.12 × 10−11 | −2.69±0.41 | 6.09 × 10−10 | −0.73±0.11 | 2.21 × 10−9 |