. Author manuscript; available in PMC: 2016 Mar 1.

Published in final edited form as: J Neuroimaging. 2014 Oct 16;25(2):200–206. doi: 10.1111/jon.12171

TABLE 1.

Demographic, clinical and MRI characteristics of the study cohort

	Relapsing remitting (n=16)	Secondary Progressive (n=9)
Age	42.06 ±6.58	45.56 ±10.11
Sex (females/males)	9/7	9/0
Years of MS	10.69 ± 5.60	17.44 ± 5.22
EDSS	2.25 (0–6.0)	6.0 (1.5–7.5)
T25WF	4.78 ± 2.03	30.41 ± 56.45
EDSS-motor	2.0 (0–4.0)	3.0 (0–5.0)
EDSS-sensory	1.5 (0–3.0)	2.0 (1.0–3.0)
Brain parenchyma fraction	0.80 ± 0.05	0.76 ± 0.04
Lesion Volumes (cm³)
cBHs (whole brain)	3.58 ±3.50	6.62 ± 3.64
T₂-lesions (whole brain)	15.47 ±10.11	16.33 ±16.39
cBHs (corticospinal tracts)	1.10 ±1.43	2.38 ± 0.97

Values are expressed in mean ± standard deviation but for the EDSS score and sub-scores for which median (minimum – maximum value) are reported. cBHs=chronic black holes; EDSS=Expanded Disability Status Scale; MS=multiple sclerosis; MRI=magnetic resonance imaging; T25FW=Timed 25-Foot Walk test.