Change from baseline to week 24 in volume (left panel) and number (right panel) of susceptibility-weighted imaging (SWI)-filtered phase white matter (WM) lesions in patients with relapsing–remitting multiple sclerosis (RRMS).
In the box plots, the yellow + represents the mean; the solid line represents the median; the dashed line represents no change; the colored boxes represent the middle 50% of data; the top and bottom of the box represent the first and third quartiles; the open circles are outliers. The ‘whisker lines’ above and below the boxes represent the largest and smallest values that are not considered to be outliers. p values shown are for the difference between RRMS and healthy controls (HCs) from the Wilcoxon rank-sum test. FLAIR, fluid-attenuated inversion recovery; NS, not significant; PD, proton density; T1WI, T1 weighted image.