Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Pharmacokinetic parameters of PPOP and reference tablets
| Formulation | Cmax (μg/mL) | Tmax (h) | T1/2 (h) | AUC (μg/mL·h) |
|---|---|---|---|---|
| Reference | 0.96±0.17 | 2.23±0.22 | 12.48±7.47 | 11.77±5.29 |
| Osmotic pump | 0.74±0.31 | 5.12±0.37 | 21.72±6.32 | 18.87±3.84 |
Note: Values are expressed as mean ± SD (n=6).
Abbreviations: AUC, area under the plasma concentration–time curve; Cmax, maximum plasma concentration; T1/2, half-life; Tmax, the time to reach Cmax; PPOP, push–pull osmotic pump; SD, standard deviation.
