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. 2015 Mar 5;10:1819–1830. doi: 10.2147/IJN.S78895

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© 2015 Yousaf et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Mean plasma level–time profiles of fenofibric acid in rats after the oral administration of various formulations.

Notes: (a) Fenofibrate powder, (b) PVP nanospheres, (c) HP-β-CD nanocorpuscles, and (d) gelatin nanocapsules. Each dose was equivalent to 20 mg/kg fenofibrate. Each value designates the mean ± SD (n=6). At all of the time points, each fenofibrate-loaded nanoparticulated formulation showed P<0.05 compared to the drug powder. *P<0.05 for gelatin nanocapsules compared with the other formulations.

Abbreviations: PVP, polyvinylpyrrolidone; HP-β-CD, hydroxypropyl-β-cyclodextrin; SD, standard deviation.