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. 2015 Mar 5;10:1769–1790. doi: 10.2147/IJN.S63155

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© 2015 Zia et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Size distribution and morphology of AmB–PGA nanoparticles.

Notes: (A) The Z-average diameter of the AmB–PGA nanoparticles determined by dynamic light scattering measurements was 107±0.7 nm. (B) Transmission electron microscopy showed that the AmB–PGA nanoparticles were spherical in shape with an average size of 98±2 nm. (C) Particle size distribution of AmB–PGA nanoparticles assessed by photon correlation spectroscopy. (D1) Phase contrast light and (D2) fluorescence micrographs of normal peritoneal macrophages after their interaction with calcein (fluorescent probe)-loaded PGA nanoparticles.

Abbreviations: AmB, amphotericin B; PGA, polyglutamic acid.