Table 2.
Groups | Creatinine (mg/dL) | ALT (IU/L) | AST (IU/L) | BUN (mg/dL) |
---|---|---|---|---|
Healthy control | 0.18±0.01 | 30.2±5.90 | 97.5±8.19 | 21.6±1.4 |
AmB-D (5 mg/kg BW) | 0.51±0.13 | 91.0±32.89 | 222.0±50.91 | 56.9±3.5 |
AmB–PGA (5 mg/kg BW) | 0.12±0.02 | 32.0±5.09 | 130.21±6.29 | 20.8±0.07 |
AmB–PGA (10 mg/kg BW) | 0.20±0.07 | 28.2±0.04 | 128.0±2.10 | 26.9±2.1 |
AmB–PGA (15 mg/kg BW) | 0.22±0.03 | 36.7±1.34 | 139.0±2.56 | 22.1±0.5 |
Abbreviations: AmB, amphotericin B; AmB-D, Fungizone®; ALT, alanine transaminase; AST, aspartate transaminase; BUN, blood urea nitrogen; BW, body weight; PGA, polyglutamic acid.