Table 3.
Kaplan–Meier analysis of clinical features in ESCC patients
| Median OS (months) | P | Median PFS (months) | P | |
|---|---|---|---|---|
| Age | ||||
| ≤56 years | 31 | 31 | ||
| >56 years | 23 | 0.023 | 18 | 0.017 |
| Sex | ||||
| Male | 21 | 18 | ||
| Female | 51 | 0.000 | 48 | 0.001 |
| Smoking status | ||||
| Yes | 23 | 19 | ||
| No | 36 | 0.263 | 30 | 0.294 |
| Tumor differentiation | ||||
| G1 | 22 | 13 | ||
| G2 | 31 | 28 | ||
| G3 | 18 | 0.369 | 18 | 0.289 |
| Infiltration depth | ||||
| Submucosa | 31 | 31 | ||
| Superficial myoinvasion | 26 | 25 | ||
| Deep myoinvasion | 48 | 41 | ||
| Full thickness | 20 | 0.044 | 18 | 0.063 |
| Lymph node status | ||||
| Negative | 37 | 30 | ||
| Positive | 18 | 0.316 | 18 | 0.532 |
| General classification | ||||
| Ulcerative type | 31 | 30 | ||
| Medullary type | 19 | 18 | ||
| Fungating type | 48 | 0.009 | 31 | 0.008 |
| Treatment | ||||
| Surgery alone | 18 | 18 | ||
| Surgery + chemotherapy | 36 | 31 | ||
| Surgery + radiotherapy | 37 | 36 | ||
| Surgery + chemotherapy + radiotherapy | 18 | 0.007 | 18 | 0.014 |
| TNM staging | ||||
| I | 51 | 51 | ||
| II | 31 | 28 | ||
| III | 18 | 18 | ||
| IV | 14 | 0.003 | 14 | 0.001 |
Abbreviations: ESCC, esophageal squamous cell carcinoma; OS, overall survival; PFS, progression-free survival; TNM, tumor node metastasis.