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. 2014 Jun 3;20(2):150–151. doi: 10.1038/mp.2014.56

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Comparison of polygenetic risk scores between: (A) population-based controls vs all schizophrenia patients (SCZ); (B) patients responding to standard medication vs patients with treatment-resistant schizophrenia (TRS) requiring clozapine treatment; (C) patients responding to clozapine vs patients with extreme treatment-resistant schizophrenia (ETRS) not even responding to clozapine; (D) patients with ETRS only vs patients with ETRS and additional poor premorbid social adjustment and early and insidious disease onset (ETRS+ P-values derived from right-tailed logistic regression models).