TABLE 2.

Characteristics of 28 Ureaplasma clinical isolates from perinatal patients in Japan

Strain	MIC (μg/ml)					Amino acid change at the indicated position ina:
						GyrA		GyrB, 462	ParC				ParE, 457
	CPFX	LVFX	TFLX	GRNX	STFX	100	104		82	83	87	88
ATCC 700970	4	2	2	0.5	1
UP1	8	2	4	1	1
UP2	8	2	4	1	2
UP5	8	2	4	0.5	0.5
UP6	16	4	16	4	1
UP7	4	2	4	0.5	0.5
UP8	8	2	4	1	1
UP11	16	2	4	0.5	0.5
UP13	4	1	2	0.5	0.5
UP14	32	8	16	2	2
UP16	8	1	2	0.5	0.5
UP17	8	2	4	1	1
UP19	8	2	4	1	0.5
UU1	8	1	8	0.5	1
UU2	16	2	8	0.5	1
UU3	16	4	8	0.5	1
UU4	16	4	8	0.5	1
UU5	16	4	8	0.5	1
UU7	16	4	16	0.5	2
UU9	16	4	8	1	1
S83L strains
UP3	128	16	>128	2	1					Leu
UP4	64	16	32	2	1					Leu
UP9	64	16	64	4	2					Leu
UP10	32	8	16	2	1					Leu
UP12	64	8	32	2	1					Leu
UP15	64	16	64	4	2					Leu
UP18	32	8	32	1	1					Leu
UU6	64	8	>128	2	4					Leu
UU8	64	8	>128	1	2					Leu

^aAmino acid position where an amino acid change is reported in quinolone-resistant mutants of U. parvum and/or U. urealyticum.