TABLE 3.
Amino acid substitutions and DNA mutations of QRDRs of Ureaplasma spp. among 130 DNA samples
| Protein | Position | Amino acid | DNA sequence |
U. urealyticum (n = 24) |
U. parvum (n = 106) |
||||
|---|---|---|---|---|---|---|---|---|---|
| Amino acid substitution | DNA mutation | No. of mutant strains | Amino acid substitution | DNA mutation | No. of mutant strains | ||||
| GyrA | 100 | Gln | 0 | 0 | |||||
| 104 | Gln | 0 | 0 | ||||||
| 112 | Glu/Asp | GAA/GAC | 0 | His | CAC | 1 | |||
| GyrB | 462 | Pro | CCA | 0 | Ser | TCA | 1 | ||
| ParC | 82 | Asp | 0 | 0 | |||||
| 83 | Ser | TCA | Leu | TTA | 3 | Leu | TTA | 25 | |
| Trp | TGAa | 1 | |||||||
| 84 | Ser | TCA | 0 | Pro | CCA | 1 | |||
| 87 | Glu | 0 | 0 | ||||||
| 88 | Ala | 0 | 0 | ||||||
| ParE | 457 | Ala | 0 | 0 | |||||
a
The TGA codon encodes tryptophan in the Mycoplasmataceae (22).