TABLE 1.

Sensitivities of the P. falciparum Dd2, Tm90-C2B, and D1 strains to ATV, ELQ-300, CQ, and the canonical Q_i and Q_o site inhibitors antimycin A and myxothiazol^a

Compound	IC50 value (nM) or ratio forb:
	Dd2	Tm90-C2B	C2B/Dd2	D1	D1/Dd2
ATV	0.4	>2,500	>7,800	0.7	1.7
ELQ-300	6.6	4.6	0.7	160	24
CQ	71	91	1.3	110	1.5
Antimycin A	72	39	0.5	35	0.5
Myxothiazol	1.7	320	190	3.5	2.0

^aATV, atovaquone; CQ, chloroquine.

^bIC₅₀ values were averaged from ≥3 independent experiments run in triplicate. The standard deviations were <10%.