FIG 1.

Intraosteoblastic inoculum change and intracellular proportion of small-colony variants in the presence of the main antistaphylococcal molecules at the usual bone concentration. The change in the number of intracellular CFU (Δlog CFU; means and 95% CI) at 2 h, starting from an initial intracellular inoculum of 1.8 × 10⁶ (95% CI =1.4 × 10⁶ to 2.1 × 10⁶) for 100,000 osteoblasts, was compared to untreated cells (Mann-Whitney U-test). CI, confidence interval; SCV, small-colony variants; **, P < 0.01; ***, P < 0.00.