FIG 3.
Dose effect of the main antistaphylococcal molecules on the intraosteoblastic emergence of small-colony variants. The change in the number of intracellular CFU (Δlog CFU; means and 95% CI) at 2 h, starting from an initial intracellular inoculum of 1.8 × 106 (95% CI = 1.4 × 106 to 2.1 × 106) for 100,000 osteoblasts, was compared to untreated cells (Mann-Whitney U-test). The dose effect was assessed using linear regression between the three used concentrations. CI, confidence interval; SCV, small-colony variants; *, P < 0.05.