TABLE 1.
Demographic and baseline characteristics of the study patientsa
| Characteristic | No. | Mean ± SD | Minimum | Median | Maximum |
|---|---|---|---|---|---|
| Sex (male/female) | 22/14 | ||||
| Race (white/Hispanic/black/other) | 22/8/4/2 | ||||
| Age (yrs) | 50.4 ± 8.6 | 27 | 52 | 61 | |
| Wt (kg) | 82.5 ± 17.9 | 56 | 79 | 128 | |
| Height (cm) | 172 ± 10 | 154 | 172 | 191 | |
| Hemoglobin (g/dl) | 15.5 ± 1.4 | 12.9 | 15.7 | 17.7 | |
| Serum creatinine (mg/dl) | 0.85 ± 0.16 | 0.51 | 0.87 | 1.20 | |
| Creatinine clearance (ml/min) | 102 ± 27 | 52.1 | 97.7 | 176.8 | |
| Viral genotype (1A/1B/1) | 16/12/8 | ||||
| ITPA phenotype (wild type/variant) | 26/10 | ||||
| IL28B genotype (CC/CT/TT/unknown) | 12/10/12/2 |
a
Creatinine clearance was calculated based on total body weight using the Cockcroft-Gault equation. CC, both copies of the gene contain the “C” allele; CT, one copy of the gene contains the “C” allele and the other the “T” allele; TT, both copies of the gene contain the “T” allele.