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. 2015 Mar 11;59(4):1950–1961. doi: 10.1128/AAC.03972-14

FIG 9.

FIG 9

TEM images of intracellular amastigotes treated with SQ109 or SQ109 plus posaconazole for 96 h. (A) Untreated intracellular amastigotes. Intracellular amastigotes treated with 1.5 μM SQ109 caused alterations in Golgi complex cisternae (arrows) (B) and formation of structures similar to autophagosomes (stars) (C). (D) Treatment of intracellular amastigotes with 0.25 nM posaconazole plus 0.4 μM SQ109 shows mitochondrial swelling and numerous vesicles in the flagellar pocket. k, kinetoplast; n, nucleus; G, Golgi; fp, flagellar pocket.