FIG 3.

Effect of DNAC-1 on cell wall, as observed by TEM. USA300 cells were grown to mid-log phase and treated with DNAC-1 for 90 min or left untreated (control). The cells were then collected and processed for EM, as described in Materials and Methods. (A) Mesosome-like invaginations are seen both along the cell wall (arrow, center) and along the septum (arrow, right). (B) DNAC-1-treated cells have a significantly thicker cell wall. as demonstrated in the box-and-whisker plot showing the standard deviation. The asterisk represents a statistically significant difference, at a P value of <0.05, comparing the control to DNAC-1-treated cells.