TABLE 2.
MIC and MBC values and the associated FICI and FBCI of two-drug combinations for M. avium
| Drug combinationa | FICI |
FBCI |
||||
|---|---|---|---|---|---|---|
| MIC (mg/liter) | Value | Interpretation | MBC (mg/liter) | Value | Interpretation | |
| RIF-EMB | 4/2 | <0.325 | Synergism | >16/2 | 2 | No interaction |
| RFP-EMB | 0.5/4 | <0.325 | Synergism | 4/1 | <0.5 | Synergism |
| MXF-EMB | 2/0.5 | 0.325 | Synergism | 2/2 | 0.625 | No interaction |
| MXF-CLR | 2/0.125 | 1.1 | No interaction | 2/0.125 | 1.1 | No interaction |
a
RIF, rifampin; RFP, rifapentine; CLR, clarithromycin; MXF, moxifloxacin; EMB, ethambutol.