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Upregulation of acrA, acrB, and oprM mRNA expression of M. catarrhalis strains O35E and 300 during amoxicillin treatment. Quantitative real-time PCR was performed after 4 h of incubation with and without 60 μg/ml amoxicillin. Upregulation was normalized to 16S rRNA. The graph shows one of two representative experiments done in triplicate. Data are presented as means ± 1 SD.
