Compounds utilized in primaquine pharmacokinetic study. The structures of primaquine (PQ), carboxy-primaquine (CPQ), and 2, 3, and 4 hydroxylated primaquine (OH-PQ) are shown. The marker for 5-hydroxylation (5,6-ortho-quinone) is also shown. The quinoline rings of PQ and the hydroxylated metabolites are numbered for reference.