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Ratios of the MICs obtained in the different strains isolated in the reversion study of the E79G mutant for compounds 1 and 2 in relation to those for the wild-type and polymorphism in codon 79 of the gyrA gene
| Compound | MICmut/MICH37Rv ratio for strain: |
|||||
|---|---|---|---|---|---|---|
| H37Rv | E79G mutant | Single crossover | Double crossover |
|||
| Clon 6 | Clon 8 | Clon 31 | ||||
| 1 | 1 | 128 | 32 | 1 | 32 | 1 |
| 2 | 1 | 32 | 16 | 2 | 16 | 1 |
| Ofloxacin | 1 | 2 | 1 | 1 | 1 | 1 |
| gyrA codon 79 polymorphism | GAG | GGG | NDa | GAG | GGG | GAG |
ND, not determined.
