Table 4.

Association¹ between GPR50 polymorphisms and the incidence of depression over 12-years in women not depressed at baseline (n = 415)

	12-year incident depression				Multivariate adjusted1
	No, N	Yes, N	Chi-squared2	P	HR (95% CI	Chi-squared2	P
rs13440581: GG	87	50	2.64	0.27	1
GA	97	81			1.39 (0.98–1.99)	3.32	0.07
AA	57	43			1.32 (0.87–1.99)	1.70	0.19
rs2072621: CC	70	66	3.64	0.16	1
AC	117	73			0.76 (0.54–1.06)	2.67	0.10
AA	54	35			0.79 (0.52–1.19)	1.26	0.26
rs561077: AA	82	54	8.31	0.01	1
GA	126	77			0.94 (0.66–1.33)	0.12	0.73
GG	33	43			1.77 (1.18–2.67)	7.54	0.006

¹Adjusted for age, education, incapacities, MMSE, and cardiovascular ischemic pathologies.

²Two degrees of freedom.