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. 2014 Nov 7;30(1):57–70. doi: 10.1007/s10654-014-9966-4

Table 3.

Risk of overall mortality in relation to fish consumption in quintiles (third quintile as reference), and as a continuous variable with 10 g increment

Q1 Q2 Q3 Q4 Q5 Continuous, 10 g increment
Male
Total fish consumption (g/d) 1.9 10.8 21.1 34.2 76.2
N cases 2,427 2,769 3,334 3,407 3,047 14,984
HR crudea 0.98 (0.77–1.26) 0.98 (0.78–1.22) Ref 1.11 (0.91–1.35) 1.08 (0.86–1.35) 1.01 (1.00–1.02)
HR uncalibrated 1.04 (0.97–1.12) 1.05 (0.97–1.12) Ref 1.05 (0.98–1.11) 1.16 (1.08–1.24) 1.01 (1.01–1.02)
HR calibrated 0.96 (0.85–1.08) 0.95 (0.84–1.07) Ref 1.02 (0.91–1.16) 1.04 (0.93–1.18) 1.01 (1.00–1.03)
Lean fish consumption (g/d) 0.1 4.0 11.8 20.6 50.4
N cases 2,217 1,782 2,283 3,378 2,764 12,424
HR crudea 1.14 (1.04–1.25) 1.14 (1.04–1.24) Ref 1.08 (1.00–1.16) 1.16 (1.07–1.25) 1.01 (1.00–1.02)
HR uncalibrated 1.14 (1.04–1.25) 1.11 (1.02–1.22) Ref 1.10 (1.02–1.18) 1.19 (1.10–1.28) 1.02 (1.00–1.03)
HR calibrated 0.96 (0.84–1.10) 0.98 (0.85–1.12) Ref 1.01 (0.88–1.16) 1.01 (0.89–1.16) 1.02 (0.98–1.05)
Fatty fish consumption (g/d) 0.1 2.9 7.8 14.1 35.6
N cases 2,648 2,150 2,666 2,409 2,551 12,424
HR crudea 1.00 (0.93–1.08) 1.00 (0.92–1.09) Ref 0.91 (0.84–0.98) 0.99 (0.92–1.07) 1.00 (0.98–1.01)
HR uncalibrated 0.98 (0.91–1.06) 0.98 (0.90–1.06) Ref 0.93 (0.86–1.00) 1.02 (0.94–1.10) 1.00 (0.99–1.02)
HR calibrated 1.10 (0.97–1.25) 1.07 (0.94–1.22) Ref 1.08 (0.95–1.23) 1.06 (0.93–1.21) 1.00 (0.97–1.03)
Female
Total fish consumption (g/d) 1.9 10.8 21.1 34.2 76.2
N cases 3,403 3,383 3,728 3,690 3,399 17,603
HR crudea 1.04 (0.68–1.58) 0.99 (0.75–1.31) Ref 0.96 (0.74–1.25) 0.97 (0.65–1.45) 1.00 (0.99–1.01)
HR uncalibrated 1.07 (1.00–1.15) 1.03 (0.96–1.10) Ref 0.99 (0.93–1.05) 1.03 (0.96–1.10) 1.00 (0.99–1.01)
HR calibrated 1.05 (0.94–1.18) 0.99 (0.88–1.10) Ref 1.02 (0.91–1.14) 1.06 (0.95–1.18) 1.01 (0.98–1.03)
Lean fish consumption (g/d) 0.1 4.1 11.5 20.5 52.0
N cases 3,525 3,131 2,979 3,556 2,910 16,101
HR crudea 1.12 (1.05–1.20) 1.05 (0.98–1.13) Ref 0.99 (0.93–1.06) 1.04 (0.96–1.11) 1.00 (0.99–1.01)
HR uncalibrated 1.10 (1.03–1.18) 1.05 (0.98–1.13) Ref 1.00 (0.94–1.07) 1.04 (0.97–1.12) 1.00 (0.99–1.01)
HR calibrated 1.05 (0.94–1.16) 0.99 (0.89–1.10) Ref 1.01 (0.91–1.12) 1.01 (0.91–1.12) 1.00 (0.97–1.03)
Fatty fish consumption (g/d) 0.2 2.9 7.7 14.1 33.9
N cases 3,602 3,245 3,376 3,101 2,777 16,101
HR crudea 1.11 (1.04–1.19) 1.07 (1.00–1.14) Ref 0.97 (0.91–1.03) 1.01 (0.94–1.08) 1.00 (0.98–1.01)
HR uncalibrated 1.09 (1.02–1.17) 1.06 (0.99–1.13) Ref 0.98 (0.92–1.05) 1.03 (0.96–1.10) 1.00 (0.99–1.02)
HR calibrated 1.03 (0.92–1.15) 1.01 (0.90–1.13) Ref 0.93 (0.83–1.04) 1.09 (0.97–1.22) 1.01 (0.97–1.06)

Data for males and females are presented separately, with 99 % confidence intervals, statistically significant results in bold

Adjusted for energy from fat, energy from carbohydrates and proteins, dietary fibres, red meat, processed meat, vegetables, fruit, alcohol intake, body mass index, physical activity, smoking, education. Lean and fatty fish were mutually adjusted for

aStratified on age, unadjusted, uncalibrated