Table 4.
Logistic regression analysis of risk factors for corticosteroid dependence at one month after start of corticosteroid
|
P value1 |
OR (95%CI) | ||
| Univariate | Multivariate | ||
| Sutherland score (≥ 6) | 0.037 | 0.014 | 2.347 (0.935-5.890) |
| Abnormal neutrophil% | 0.016 | 0.107 | 0.425 (0.168-1.075) |
| Weight loss | 0.021 | 0.336 | 2.400 (0.839-6.866) |
| Mucus | 0.096 | ||
| Diarrhea (> 6/d) | 0.136 | ||
| Hypokalemic (< 3.5 mmol/L) | 0.176 | ||
| ESR (> 15 mm/h) | 0.186 | ||
| Bloody stool | 0.343 | ||
1
Data with univariate P < 0.5 are not displayed. All the variables were statistically analyzed. In univariate analysis, Sutherland score (≥ 6), abnormal neutrophil% and weight loss after one month of corticosteroid treatment were related with corticosteroid dependence (P = 0.037, 0.016, 0.021). All the variables with P < 0.100 were further analyzed by logistic regression. After multivariate analysis, sustained high Sutherland score (≥ 6) after one-month treatment was found to be associated with corticosteroid dependence (OR = 2.347; 95%CI: 0.935-5.890; P = 0.014).