Change of WBC count in Yucatan minipigs exposed to pSPE radiation or eSPE
radiation. A minimum of 3 animals per group were exposed to pSPE radiation (A)
at a single skin dose of 5 (solid circle), 7.7 (unfilled circle) or 10 (filled
triangle) Gy or eSPE radiation (B) at a single skin dose of 5 (solid circle),
7.5 (unfilled circle), 10 (filled triangle), and 20 Gy (unfilled triangle). The
WBC count was determined at the indicated time points. The results are expressed
as fraction of control and compared with the pre-irradiation baseline value
(indicated by dashed line). Statistical significance of the comparison is
indicated by an x (p is between 0.005 and 0.10, and considered as marginally
significant), * (p < 0.05), ** (p < 0.01) and *** (p <
0.001), as appropriate. Each data point represents a mean of three animals, and
the associated standard error is indicated by the error bar.