Table 1. Gene expression of human ABC transporters in ocular tissues.
| Gene | Alias | Probeset | Trabecular meshwork | Ciliary body | Optic nerve | Optic nerve head |
|---|---|---|---|---|---|---|
| ABCB1 |
P-glycoprotein/MDR1 |
3,060,182 |
33.27 |
23.14 |
30.13 |
45.95 |
| ABCC1 |
MRAP-1 |
3,649,890 |
28.76 |
26.45 |
26.75 |
24.73 |
| CYP3A5 | Cytochrome P450 3A5 | 3,063,406 | 31.92 | 32.63 | 28.74 | 37.14 |
Level of expression of ABC transporters was determined from the Ocular Tissue Database, a collection of data using Affymetrix Human Exon 1.0 ST arrays. Probe Logarithmic Intensity ERror (PLIER) values were used to determine significance of expression for ABCB1 and ABCC1 transporters. *Remaining 46 human ABC transporters were determined to have notable expression using a threshold ≥30 PLIER value.