Table 1.

Percent of occurrence and transition probabilities

Parameter	Percent	Weekly transition probability
CCO + SSD healing rate*
Weeks 1, 6, 9, and 11	5.0	0.05
Weeks 2, 4, and 12	10.0	0.10
Weeks 3, 5, 7, 10, and 19-52	0.0	0.00
Week 8	15.0	0.15
Weeks 13-18	6.9	0.07
Control healing rate*
Weeks 1-2, 4, 6-7, 9, 11, and 26-52	0.0	0.00
Week 3	15.0	0.15
Weeks 5 and 10	5.0	0.05
Weeks 8 and 12	11.0	0.11
Weeks 13-25	5.6	0.06
Ulcer recurrence †
Weeks 1-52	47.1	0.01
All-cause mortality ‡	0.0147	<0.01

CCO, clostridial collagenase ointment; SSD, serial sharp debridement.

*NCT01408277, Briggs et al. [31-33].

^†Persson et al. [34].

^‡Centers for Disease Control for 2010 for persons 35–95 years [30].