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. 2015 Mar 13;46:31. doi: 10.1186/s13567-015-0163-6

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© Zhang et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Quantitative analysis of defined cell populations with immunohistochemistry. (A-B) Shown are the average (± SD) numbers of cells/ High Power Field, including T cells (CD3-positive) and B cells (CD20-positive) in the corpus of the stomach of mice. (C-D) Shown are the average (± SD) numbers of epithelial cells in five randomly chosen microscopic fields at the level of the gastric pits in the stomach from mice and Mongolian gerbils. An * represents a statistically significant difference (p < 0.05) between infected and control groups. An a represents a statistically significant difference (p < 0.05) between WT Helicobacter infected groups and isogenic ggt mutant infected groups. Ctr: animals from control group; HS: animals infected with WT H. suis strain HS5cLP; HSm: animals infected with H. suis strain HS5cLPΔggt; SS1: animals infected with WT H. pylori SS1; SS1m: animals infected with H. pylori SS1Δggt; PMSS1: animals infected with WT H. pylori PMSS1; PMSS1m: animals infected with H. pylori PMSS1Δggt; WT: wild-type; 3w: 3 weeks post infection; 9w: 9 weeks post infection; 6 m: 6 months post infection.