Table 5.
Logistic regression models for predicting TLS formation in breast carcinomas
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| OR | 95% CI | pvalue | OR | 95% CI | pvalue | |
| Tumor size (≤20 / 21–50 / >50 mm) | ||||||
| ≤20 mm | 1.00 | (Reference) | 1.00 | (Reference) | ||
| 21 - 50 mm | 1.40 | 0.82 - 2.40 | 0.22 | 0.84 | 0.42 - 1.70 | 0.63 |
| >50 mm | 0.20 | 0.02 - 1.59 | 0.13 | 0.14 | 0.01 - 1.42 | 0.09 |
| Tumor grade (I / II / III) | ||||||
| Grade 1 | 1.00 | (Reference) | 1.00 | (Reference) | ||
| Grade 2 | 2.02 | 1.08 - 3.80 | <0.05 | 1.53 | 0.72 - 3.26) | 0.27 |
| Grade 3 | 6.53 | 2.96 - 14.40 | <0.01 | 2.78 | 1.06 - 7.27 | <0.05 |
| Immune cell infiltration (low / high) | 13.97 | 7.78 - 25.09 | <0.01 | 10.80 | 5.54 - 21.05 | <0.01 |
| Lymph node (− / +) | 1.65 | 0.99 - 2.76 | 0.057 | 0.98 | 0.47 - 2.02 | 0.95 |
Abbreviations: OR odds ratio, CI confidence interval.