Table 5.
Unadjusted and multivariable-adjusted odds ratios comparing ICU day 1 hCAP18 levels and secondary outcomes
| Outcome | Unadjusted | Adjusted | ||
|---|---|---|---|---|
| Odds ratio (95% CI) | P value | Odds ratio (95% CI) | P value | |
| Hospital mortality (9 events) | ||||
| Tertile 1 | 2.17 (0.37-12.55) | 0.39 | 1.97 (0.33-11.75) | 0.46 |
| Tertile 2 | 1.58 (0.25-10.00) | 0.63 | 1.66 (0.26-10.78) | 0.60 |
| Tertile 3 (REF) | 1.00 | N/A | 1.00 | N/A |
| Sepsis (71 events) | ||||
| Tertile 1 | 2.35 (0.96-5.74) | 0.06 | 2.54 (1.01-6.4) | 0.047 |
| Tertile 2 | 3.72 (1.47-9.45) | 0.006 | 3.64 (1.40-9.44) | 0.008 |
| Tertile 3 (REF) | 1.00 | N/A | 1.00 | N/A |
| AKI (33 events) | ||||
| Tertile 1 | 0.65 (0.22-1.96) | 0.45 | 0.61 (0.20-1.88) | 0.39 |
| Tertile 2 | 2.06 (0.78-5.45) | 0.15 | 2.01 (0.74-5.46) | 0.17 |
| Tertile 3 (REF) | 1.00 | N/A | 1.00 | N/A |
Adjusted models include age and APACHE II score. ICU, intensive care unit; hCAP18, human cathelicidin antimicrobial protein-18; CI, confidence interval; AKI, acute kidney injury; APACHE II, Acute Physiology and Chronic Health Evaluation II.