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Calculated creatinine clearance (CrCl) over time by treatment group. Continuous line represents treatment arm A (zidovudine/lamivudine + efavirenz [ZDV/3TC + EFV]) dotted line represents treatment arm C (tenofovir/emtricitabine + efavirenz [TDF/FTC + EFV]). Statistically significant differences in CrCl were found at week 24, 48, 72, 144, and 192 by Wilcoxon test.
