Fig. 4.

Histological scores of loss of epithelium (a), crypt damage (b), depletion of goblet cells (c), and infiltration of inflammatory cells (d)

Rats were treated intrarectally with 4% acetic acid (AA) alone (A) or after 7 consecutive days of treatment with 100 mg/kg sodium butyrate orally (ABO), intrarectally (ABR), or intraperitoneally (ABP). Results are expressed as mean±SEM of at least 8 individual rats. ^* Significantly different from AA exposed rats (P<0.05); ^# Significantly different from another routes of butyrate administration at P<0.05; ^Φ Significantly different between oral and intrarectal butyrate at P<0.05