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. 2015 Mar 12;11(3):e1005024. doi: 10.1371/journal.pgen.1005024

Fig 1. Regional association plot for ISL1 across a 1.0 Mb window.

Fig 1

Association with classic bladder exstrophy of individual SNPs in the meta-analysis GWAS is plotted as −log10(p) against chromosomal position. The y-axis on the right shows the recombination rate estimated from the 1000 Genomes (Mar 2012) EUR populations. All P values (y-axis on the left) are from the meta-analysis. The purple diamond indicates the most significant marker.