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. Author manuscript; available in PMC: 2015 Mar 12.
Published in final edited form as: Obesity (Silver Spring). 2009 Jan 15;17(4):729–736. doi: 10.1038/oby.2008.593

Table 1. Subject Characteristics.

GDM probands Siblings Cousins
Male/female 0/118 150/229 95/125
Age (years) 35.8 (5.8) 35.1 (8.7) 33.0 (9.2)*,**
BMI (kg/m2) 32.5 (7.0) 29.9 (6.1)* 28.6 (6.4)*,**
Body fat (%) 39.2 (5.3) 32.8 (8.5)* 30.9 (8.6)*,**
Fasting glucose (mmol/l) 5.4 (0.6) 5.2 (0.5)* 5.1 (0.6)*
Two-hour glucose (mmol/l) 9.2 (2.3) 7.7 (2.2)* 6.9 (2.0)*,**
Fasting insulin (pmol/l) 83 (57) 62 (45)* 59 (52)*
30′ Insulin (pmol/l) 500 (322) 524 (346) 549 (368)
Two-hour insulin (pmol/l) 721 (500) 526 (411)* 451 (385)*,**
SG (×10-2 min-1) 1.48 (0.48) 1.71 (0.68)* 1.83 (0.71)*,**
SI (×10-3 min-1 per pmol/l) 2.76 (1.76) 2.94 (1.63) 3.16 (1.73)*
AIR (pmol/l × 10 min) 4171 (4281) 5678 (4521)* 6245 (5285)*
Disposition index 8694 (5829) 14055 (9579)* 15710 (9394)*,**

Values are unadjusted median and interquartile range.

AIR, acute insulin response; GDM, gestational diabetes mellitus; SG, glucose effectiveness; SI, insulin sensitivity.

*

Uncorrected P < 0.05 vs. probands.

**

Uncorrected P < 0.05 vs. siblings.