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. 2015 Mar 12;350:h1109. doi: 10.1136/bmj.h1109

Table 1.

 Characteristics of randomised controlled trials of varenicline 1mg twice daily included in systematic review

Study Duration (weeks) Sample size Mean age (years) % Men % White
Study Treatment Varenicline Placebo Varenicline Placebo Varenicline Placebo Varenicline Placebo
Anthenelli, 201324 52 12 256 269 45.4 47.1 37.9 36.8 NA NA
Bolliger, 201125 24 12 394 199 43.1 43.9 57.7 65.7 30.3 31.3
Brandon, 201126 2.2 2.2 56 58 45.8 41.2 60.9 61.1 54.1 64.8
Burstein, 200627 1.3 1.3 8 8 68.1 67.9 75 50 50 37.5
Chengappa, 201466 24 12 31 29 45.7 46.2 29 34.5 64.5 72.4
Cinciripini, 201328 24 12 86 106 43.8 45.2 61.6 63.2 58.1 71.7
Ebbert, 201129 24 12 38 38 40.7 41 100 100 100 100
Evins, 201430 64 40 40 47 51.4 45.7 60 66 75 72
Faessel, 200931 2.6 2 14 7 15.4 15.4 57.1 57.1 85.7 71.4
Fagerstrom, 201032 26 12 213 218 43.9 43.9 89 90 99 100
Fatemi, 201333 12 12 6 9 40.4 41.4 83.3 77.8 50 88.9
Garza, 201134 16 12 55 55 33.4 33.8 60 72.7 80 70.9
Gonzales, 200635 52 12 352 344 42.5 42.6 50 54.1 79.5 76.2
Gonzales, 201467 52 12 251 247 47.7 47.3 49.8 49.4 94.8 91.4
Hughes, 201136 24 8 107 111 44 41.2 60.5 57.2 91.4 91.9
Jorenby, 200637 52 12 344 341 44.6 42.3 55.2 58.1 85.5 85
Litten, 201338 16 13 97 101 46 45 73.2 68.3 61.9 70.3
McClure, 201339 5 5 54 50 45 43 40 59 32 36
McKee, 200940 1.1 1 10 10 34.2 35.3 80 80 40 90
Meszaros, 201341 12 8 5 5 42 44 80 60 40 60
Mitchell, 201242 16 12 33 31 29 25 55 65 73 64
Nakamura, 200743 52 12 156 154 40.1 39.9 79.2 76 NA NA
Niaura, 200844 40 12 160 160 41.5 42.1 50.3 53.5 93 88.4
Nides, 200645 52 7 127 127 41.9 41.6 50.4 52 85.6 87.8
Oncken, 200646 52 12 259 129 42.2 43 48.5 51.9 80.8 72.1
Plebani, 201247 9 8 18 19 NA NA 69.6 75 11 33
Plebani, 201348 13 12 19 21 44.8 48.1 78.9 90.5 42.1 71.4
Poling, 201049 12 11 13 18 36.5 34.4 84.6 77.8 46.2 72.2
Rennard, 201250 24 12 493 166 43.9 43.2 60 59.6 68 68.1
Rigotti, 201051 52 12 355 359 57 55.9 75.2 82.2 80.3 80.8
Shim, 201252 8 8 60 60 39.9 39.9 38 45 0 0
Stein, 201353 24 24 137 45 39.2 40.6 46 62.2 82.5 75.6
Steinberg, 201154 24 12 40 39 NA NA 60 59 77 67
Tashkin, 201155 52 12 250 254 57.2 57.1 62.5 62.2 81.9 84.1
Tonnesen, 201356 52 12 70 69 53.6 55.6 42.9 49.3 NA NA
Tonstad, 200657 52 12 603 607 45.4 45.3 50.2 48.3 96.7 97
Tsai, 200758 24 12 126 124 39.7 40.9 84.9 92.7 0 0
Wang, 200959 24 12 165 168 39 38.5 96.4 97 0 0
Weiner, 201160 12 12 4 5 NA NA NA NA NA NA
Williams, 200761 53 52 251 126 48.2 46.6 50.6 48.4 86.9 92.1
Williams, 201262 26 12 84 43 40.2 43 77.4 76.7 59.5 58.1
Wong, 201263 52 12 151 135 51.9 53.3 55 50.4 NA NA
Zesiewicz, 201264 8 8 10 10 47.4 53.8 44 67 NA NA
Zhao, 201165 3.7 3 14 10 71 73 42.9 50 100 90

NA=not applicable.