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. Author manuscript; available in PMC: 2015 Mar 12.
Published in final edited form as: Annu Rev Nutr. 2013 Apr 29;33:45–70. doi: 10.1146/annurev-nutr-071812-161246

Figure 1.

Figure 1

Vitamin C homeostasis. Vitamin C levels in the circulation and tissues are influenced by several regulatory mechanisms in the body. Proteins involved in vitamin C homeostasis fall under the general-categories transporters (blue) that transport vitamin C across cell membranes and those that modulate oxidative stress (red) and would interact with ascorbate due to its antioxidant properties. GLUT, glucose transporter protein; GST, glutathione S-transferase; MnSOD, manganese superoxide dismutase; SVCT, sodium-dependent vitamin C transporter.